News Posts
c-myb needed for smooth muscle differentiation
Ithaca, NY - There is some evidence that bone marrow derived stem cells may transdifferentiate into muscle. In fact, several pieces of evidence suggest that bone marrow stem cells may help to heal injured heart muscle. If stem cells are to be used for generation of muscle...Sunday January 13th, 2008 @ 23:24:40 EST
HSC Transplants...young thymus helps
Osaka, Japan - It is known that as humans grow up their thymus involutes, this is particularly noticable after puberty when various hormones cause en mass death and atrophy of thymic components. Now maybe its just me, but does it not seem odd that hematopoietic stem cell transplants which require the stem cell to differentiate...Tuesday January 8th, 2008 @ 21:11:00 EST
Serum Free ES to Hepatocyte Differentiation
Tehran, Iran - The ability to differentiate embryonic stem cells into various tissues would allow for the generation of tailor-made cells that could replenish damaged organs or cells of the organs. If one is to approach this field from the outside, it makes the most sense to start not be trying to build a whole new organ, which is comprised of many cell types, extracellular matrices, and...Tuesday January 8th, 2008 @ 11:49:24 EST
TGF-beta stimulating bone marrow to cardiac in vitro
Yamaguchi, Japan - The ability of various mesenchymal stem cell populations and CD34 stem cell populations to help in stimulation of cardiac regeneration is a current belief by many investigators. Although some positive in vivo data have been generated withAutologous G-CSF mobilized CD34 for angina
Chicago, IL - The use of stem cells for myocardial repair was originally proposed after mouse studies demonstrated what appeared to be human bone marrow derived stem cells differentiating into myocardium. Subsequently, these experiments were translated into clinical studies, which utilized autologous bone marrow cells as sources of...Friday December 28th, 2007 @ 22:54:26 EST
Mobilized Stem Cells for Peripheral Artery Disease
Hangzhou, China - The use of autologous bone marrow stem cells for peripheral artery disease is occuring in the US as part of clinical trials. The rational is that insertion of stem cells into ischemic muscle leads to angiogenesis either through the endothelial precursor...Friday December 21st, 2007 @ 11:56:59 EST
PPAR gamma agonists: inhibition of fibrosis
Rochester, NY - The understanding how to modulate the balance between generation of new functional tissue and creation of a fibrotic scar would allow for the treatment of numerous conditions associated with scar tissue deposition. It is known that stem cells can help to heal scarred tissue ranging from myocardium, to
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IL-10 in healing of nerves
Sheffield, UK - There seems to be some connections between the immune system and various stem cell niches. For example, while the role of the stromal cells is to provide nutrients for the bone marrow hematopoietic stem cells, these cells also play anti-inflammatory functions. In some situations activations of enzymes associated...Thursday December 20th, 2007 @ 01:37:35 EST
Cardiac Stem Cell Migration Dependent on p38
Wuhan, China - Many tissues have tissue resident stem cells. Although not in high numbers, these stem cells have nevertheless been demonstrated to play at least some role in regeneration after injury. Stem cells in tissues can be isolated by their side population characteristics, or by their expression ofEmbryonic stem cells into urinary epithelium
Asahi, Japan - Generation of three dimensional structures that can be implanted into patients is one of the exciting prospects offered by stem cell technologies. For example, three dimensional structures such as heart valves and "uteri"https://www.stemcellpatents.com/patents-show-51 have already been engineered in vitro. One...Wednesday December 19th, 2007 @ 11:08:06 EST