Patents (1436 Stem Cell Patents)

Class: Type (195)

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Cells producing stem cell proliferation factor

Patent Number: 5650299

This patent covers a cell line that produces a factor associated with inducing proliferation of stem cells. If this factor is not already commercialized, which it appears it is not, this patent is a great tool for starting a biotech company.

Inventors: Lawman, Michael J. P. (Orlando, FL); Lawman, Patricia D. (Orlando, FL); Denslow, Nancy D. (Gainesville, FL)
Assignee: The University of Florida (Gainesville, FL)
Date of First Priority Issue: Wednesday October 6th, 1993

Stromal cell lines from human bone marrow and their use

Patent Number: 5658761

This patent covers immortalized stromal cells, which can be used for gene therapy. These stromal cells appear to be similar to mesenchymal stem cells in some ways.

Inventors: Thalmeier, Karin (Munchen, DE); Dormer, Peter (Gilching, DE)
Assignee: Gsf-Forschungszentrum fur Umwelt und Gesundheit GmbH (OberscheleiBheim, DE)
Date of First Priority Issue: Wednesday July 7th, 1993

Use of neuro-glial cell lines for transplantation therapy

Patent Number: 5869463

This patent covers a type of stem cell that is isolated from fetal brain that is useful for the treatment of neurodegenerative disease.

Inventors: Major, Eugene O. (Oakton, VA); Tornatore, Carlo S. (University Park, MD)
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, DC)
Date of First Priority Issue: Tuesday April 13th, 1993

Blood-borne mesenchymal cells

Patent Number: 6174526

This patent teaches the use of circulating mesenchymal stem cells for treatment of wounds.

Inventors: Cerami, Anthony (Shelter Island, NY); Bucala, Richard J. (New York, NY)
Assignee: The Picower Institute for Medical Research (Manhaset, NY)
Date of First Priority Issue: Friday February 26th, 1993

Blood-borne mesenchymal cells

Patent Number: 5846796

This patent covers mesenchymal stem cells that are circulating in the blood. This patent is interesting since the cells covered contain the hematopoietic stem cell marker CD34, which is usually not believed to be expressed on mesenchymal stem cells. Additionally, the marker CD45, is usually a hematopoietic associated marker, but it too is...

Inventors: Cerami, Anthony (Shelter Island, NY); Bucala, Richard J. (New York, NY)
Assignee: The Picower Institute for Medical Research (Manhasset, NY)
Date of First Priority Issue: Friday February 26th, 1993

Blood-borne mesenchymal cells

Patent Number: 5804446

This patent covers a type of stem cell that circulates and is mesenchymal in nature. The cell phenotype is CD34+ and CD45+, both being markers of hematopoietic and not classical mesenchymal stem cells.

Inventors: Cerami, Anthony (Shelter Island, NY); Bucala, Richard J. (New York, NY)
Assignee: The Picower Institute for Medical Research (Manhasset, NY)
Date of First Priority Issue: Friday February 26th, 1993

Blood-borne mesenchymal cells

Patent Number: 5654186

This patent covers a special population of stem cells that circulate in peripheral blood. Although the patent uses the word "mesenchymal" to describe the cells, these may not be true mesenchymal cells since they possess hematopoietic markers such as CD34 and CD45.

Inventors: Cerami, Anthony (Shelter Island, NY); Bucala, Richard J. (New York, NY)
Assignee: The Picower Institute for Medical Research (Manhasset, NY)
Date of First Priority Issue: Friday February 26th, 1993

Parthenogenic oocyte activation

Patent Number: 6194202

This patent covers the generation of embryonic stem cells through parthenogenesis in cows. Parthenogenesis involves activating the oocyte to differentiate in absence of sperm.

Inventors: Susko-Parrish, Joan L. (Monona, WI); Northey, David L. (Madison, WI); Leibfried-Rutledge, M. Lorraine (Madison, WI); Stice, Steven L. (DeForest, WI)
Assignee: Infigen, Inc. (DeForest, WI)
Date of First Priority Issue: Wednesday February 10th, 1993

Parthenogenic oocyte activation

Patent Number: 6077710

This patent covers the generation of embryos through virgin birth or parthenogenesis. Essentially if an oocyte is activated through the induction of calcium flux it can generate an embryo-like structure which can be used to derive stem cells.

Inventors: Susko-Parrish, Joan L. (Monona, WI); Northey, David L. (Madison, WI); Leibfried-Rutledge, M. Lorraine (Madison, WI); Stice, Steven L. (DeForest, WI)
Assignee: Infigen, Inc. (Deforest, WI)
Date of First Priority Issue: Wednesday February 10th, 1993

Parthenogenic oocyte activation

Patent Number: 5496720

Parthenogenesis comes from Greece and essentially means "virgin birth". This patent teaches how to induce parthenogenesis in a bovine oocyte through induction of calcium flux. The induction of parthenogenesis leads to activation of the oocyte and can be used as a method of generating autologous stem cells for woman.

Inventors: Susko-Parrish, Joan L. (Monona, WI); Northey, David L. (Middleton, WI); Leibfried-Rutledge, M. Lorraine (Madison, WI); Stice, Steven L. (DeForest, WI)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Wednesday February 10th, 1993

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