Patents
Matrix for the manufacture of autogenous replacement body parts
Patent Number: 5906827Disclosed are a variety of devices and matrices that are useful for generation of artifical joints through the use of stem cells and differentiated cells.
Inventors: Khouri, Roger K. (St. Louis, MO); Sampath, Kuber T. (Medway, MA); Rueger, David C. (Hopkinton, MA)
Assignee: Creative BioMolecules, Inc. (Hopkinton, MA)
Date of First Priority Issue: Friday June 3rd, 1994
Cultured inner cell mass cell lines derived from bovine or porcine embryos
Patent Number: 5905042This patent provides technologies for growing stem cells that are useful for the generation of chimeric cows or pigs.
Inventors: Stice, Steven L. (Belchertown, MA); Golueke, Paul J. (Belchertown, MA)
Assignee: University of Massachusetts, A Public Institution of Higher Education of (Amherst, MA)
Date of First Priority Issue: Monday April 1st, 1996
Identification of blast cells in a leukocyte cell preparation
Patent Number: 5905031This patent covers ways of detecting blast cells from other types of cells using photometric means.
Inventors: Kuylen, Nazle (Miami, FL); Crews, Harold R. (Pembroke Pines, FL); Jaffe, Gerald E. (Pembroke Pines, FL); Barcelon, Maria (Ft. Lauderdale, FL); Lucas, Francis J. (Boca Raton, FL); Garcia, Nancy M. (Miami, FL)
Assignee: Coulter International Corp. (Miami, FL)
Date of First Priority Issue: Thursday May 18th, 1995
Method of stimulating bone marrow regeneration
Patent Number: 5888965This patent teaches how to enhance hematopoiesis using hepatocyte growth factor alone or in combination with other cytokines.
Inventors: Kmiecik, Thomas E. (Frederick, MD); Vande Woude, George F. (Berryville, VA)
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, DC)
Date of First Priority Issue: Wednesday December 27th, 1989
Devices for maintaining and growing human stem and/or hematopoietics cells
Patent Number: 5888807This patent provides bioreactors and specialized culture vessels that are useful for the growth and expansion of human hematopoietic stem cells.
Inventors: Palsson, Bernhard O. (Ann Arbor, MI); Emerson, Stephen G. (Ann Arbor, MI); Schwartz, Richard M. (Ann Arbor, MI)
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Date of First Priority Issue: Thursday June 15th, 1989
Method for increasing neutrophil populations using in vitro-derived human neutrophil precursor cells
Patent Number: 5888499This patent covers ways of generating neutrophil-committed stem cells. These neutrophil committed stem cells are useful for prevention of infection after myeloablation.
Inventors: Bender, James G. (Lindenhurst, IL); Maples, Phillip B. (Waukegan, IL); Smith, Stephen (Arlington Heights, IL); Unverzagt, Kristen L. (Palatine, IL); Van Epps, Dennis E. (Cary, IL)
Assignee: Nexell Therapeutics Inc. (Irvine, CA)
Date of First Priority Issue: Monday March 23rd, 1992
Human marrow stromal cell lines which sustain hematopoieses
Patent Number: 5879940This patent covers a "stromal" cell line that supports hematopoiesis in vitro. I wonder how different are these "stromal" cell lines from the mesenchymal stem cells that are described by Osiris?
Inventors: Torok-Storb, Beverly (Seattle, WA); Roecklein, Bryan A. (Seattle, WA); Johnson, Gretchen (Issaquah, WA)
Assignee: Fred Hutchinson Cancer Research Center (Seattle, WA)
Date of First Priority Issue: Wednesday July 20th, 1994
Use of neuro-glial cell lines for transplantation therapy
Patent Number: 5869463This patent covers a type of stem cell that is isolated from fetal brain that is useful for the treatment of neurodegenerative disease.
Inventors: Major, Eugene O. (Oakton, VA); Tornatore, Carlo S. (University Park, MD)
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, DC)
Date of First Priority Issue: Tuesday April 13th, 1993
Submucosa gel as a growth substrate for cells
Patent Number: 5866414This patent describes compositions derived from the submucosa of various mammals that possess growth factors useful for the expansion of stem cells.
Inventors: Badylak, Stephen F. (West Lafayette, IN); Voytik, Sherry (Lafayette, Indiana, IN); Boder, George (Martinsville, IN)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Friday February 10th, 1995
Inhibitor of stem cell proliferation and uses thereof
Patent Number: 5861483This patent describes peptides derived from hemoglobin that inhibit stem cell proliferation. These peptides are useful for protecting stem cells from killing by chemotherapy or radiation therapy.
Inventor: Wolpe, Stephen D. (Rockville, MD)
Assignee: Pro-Neuron, Inc. (Rockville, MD)
Date of First Priority Issue: Wednesday April 3rd, 1996