Patents
Method for modulating smooth muscle cell proliferation
Patent Number: 6114311This patent covers promoters of smooth muscle cells, as well as promoters found in the stem cells for smooth muscle cells. The invention teaches how to use these promoters to treat various conditions ranging from restenosis to asthma.
Inventors: Parmacek, Michael S. (Chicago, IL); Solway, Julian (Glencoe, IL)
Assignee: Arch Development Corporation (Chicago, IL)
Date of First Priority Issue: Monday October 7th, 1996
Human pluripotent hematopoietic colony stimulating factor and cell line producing same
Patent Number: 6114166This patent covers a cytokine that stimulates proliferation of hematopoietic stem cells which give rise to all hematopoietic lineages.
Inventors: Welte, Karl (New York, NY); Platzer, Erich (Erlangen, DE); Gabrilove, Janice L. (New York, NY); Mertelsmann, Roland (Mainz, DE); Moore, Malcolm A. S. (Larchmont, NY)
Assignee: Sloan-Kettering Institute for Cancer Research (New York, NY)
Date of First Priority Issue: Thursday March 28th, 1985
Development and use of human pancreatic cell lines
Patent Number: 6110743This patent covers islet stem cells and cell lines that generate islet cells. This patent could be useful for the treatment of type 1 diabetes. In some cases, it may be beneficial to encapsulate the cell lines so as to avoid immune mediated rejection. Alternatively these cells would provide a great source of tissue for using the Edmonton Protocol.
Inventors: Levine, Fred (Del Mar, CA); Wang, Sijian (Dallas, TX); Beattie, Gillian M. (Poway, CA); Hayek, Alberto (La Jolla, CA)
Assignee: The Regents of the University of California (Oakland, CA); Whittier Institute for Diabetes and Endocrinology (La Jolla, CA)
Date of First Priority Issue: Friday February 10th, 1995
Method to produce novel embryonic cell populations
Patent Number: 6110739This patent covers generation of cells from embryonic stem cells, and subsequent immortalization of the generated cells. The generated cells may be semidifferentiated stem cells or precursor cells. Immortalization may be accomplished by transfection with the gene HOX 11.
Inventors: Keller, Gordon M. (Denver, CO); Hawley, Robert G. (Toronto, CA); Choi, Kyunghee (Baltimore, MD)
Assignee: National Jewish Medical and Research Center (Denver, CO)
Date of First Priority Issue: Monday November 21st, 1994
Manufacture of autogenous replacement body parts
Patent Number: 6110482This patent teaches how to make artificial joints using stem cells and various devices and systems.
Inventors: Khouri, Roger K. (St. Louis, MI); Sampath, Kuber T. (Medway, MA); Rueger, David C. (Hopkinton, MA)
Assignee: Styker Corporation (Kalamazoo, MI)
Date of First Priority Issue: Friday June 3rd, 1994
Methods for extracting bone marrow
Patent Number: 6110176This patent provides procedures and devices useful for harvesting bone marrow. In one embodiment the bone marrow is harvested from the jaw of the patient.
Inventor: Shapira, Ira L. (Highland Park, IL)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Tuesday July 1st, 1997
Culture of totipotent embryonic inner cells mass cells and production of bovine animals
Patent Number: 6107543This patent is about ways of cloning cows using stem cells harvested form the inner cell mass.
Inventors: Sims, Michelle M. (Stoughton, WI); First, Neal L. (Madison, WI)
Assignee: Infigen, Inc. (DeForest, WI)
Date of First Priority Issue: Thursday August 20th, 1992
Method for enhancing hematopoiesis with acyl deoxyribonucleosides
Patent Number: 6103701Small molecules are provided that stimulate hematopoietic stem cell proliferation. These molecules may be of interest for stimulation of non-hematopoietic stem cells.
Inventors: von Borstel, Reid Warren (Darnestown, MD); Bamat, Michael Kevin (Darnestown, MD)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Wednesday October 28th, 1987
Method of decreasing radiation of radio-mimetic chemotherapy for hematopoietic pluripotent cell engraftment
Patent Number: 6103694This patent teaches how to perform hematopoietic stem cell transplants without myeloablating the recipient. This patent provides specific doses of radiation that can mimic the effects of chemotherapy. This patent may be useful for other types of stem cell therapy in order to temporarily suppress the recipient immune system so as to allow the transplanted cells to engraft, establish themselves...
Inventors: Mardiney, III, Michael (Baltimore, MD); Malech, Harry L. (Bethesda, MD)
Assignee: The United States of America as represented by the Department of Health (Washington, DC)
Date of First Priority Issue: Friday July 21st, 1995
Cultures of human CNS neural stem cells
Patent Number: 6103530This patent provides a tissue culture media that is useful for the growth and expansion of neural stem cells.
Inventor: Carpenter, Melissa (Lincoln, RI)
Assignee: Cytotherapeutics, Inc. (Lincoln, RI)
Date of First Priority Issue: Friday September 5th, 1997