Patents
Method of preparing human stem cell factor polypeptide
Patent Number: 6759215This patent is part of the huge wall Amgen put around the IP for stem cell factor. This patent specifically encompasses the cells that are transformed with SCF genes in order to generate SCF protein. SCR is the same as kit ligand.
Inventors: Zsebo, Krisztina M. (Thousand Oaks, CA); Bosselman, Robert A. (Thousand Oaks, CA); Suggs, Sidney V. (Newbury Park, CA); Martin, Francis H. (Thousand Oaks, CA)
Assignee: Amgen Inc. (Thousand Oaks, CA)
Date of First Priority Issue: Monday October 16th, 1989
Method of identifying a neural progenitor cell by evaluating expression of daedalos
Patent Number: 6759201This patent covers a new marker for neural stem cells called Daedalos. It provides methods of using this marker for identifying and extracting neural stem cells. The neural stem cells can be used for treatment of a variety of neurological disorders such as Parkinsons, Alzheimers, etc.
Inventor: Morgan, Bruce A. (Lexington, MA)
Assignee: The General Hospital Corporation (Boston, MA)
Date of First Priority Issue: Wednesday October 25th, 2000
Culturing pancreatic stem cells having a specified, intermediate stage of development
Patent Number: 6759039This patent covers methods of culturing and expanding pancreatic stem cells. These cells may be used for the treatment of diabetes through encapsulation or administration into the liver such as thought by the Edmonton Protocol.
Inventors: Tsang, Wen-Ghih (Sherman Oaks, CA); Zheng, Tianli (Culver City, CA); Huang, Chang Jiang (Los Angeles, CA)
Assignee: AmCyte, Inc. (Santa Monica, CA)
Date of First Priority Issue: Friday June 30th, 2000
Catheter for cell delivery in tissue
Patent Number: 6758828This patent is for a medical device that can be utilized for administration of stem cells into tissues. This medical device is unique in that it contains several safety parameters that are important for regulatory approval of such administration devices.
Inventors: Hammer, Bruce E. (Minnetonka, MN); Conroy, Mark J. (St. Louis Park, MN)
Assignee: Regents of the University of Minnesota (Minneapolis, MN)
Date of First Priority Issue: Monday December 10th, 2001
Markers for identification and isolation of pancreatic islet .alpha. and .beta. progenitors
Patent Number: 6753153This patent discloses protein markers that can be used for purification of pancreatic stem cells. The markers are agents that are capable of binding the protein ErbB2. This patent may be used for purification and ex vivo expantion of islets from tissue, or may be used for characterization of islet stem cells generated via embryonic or other type of stem cell culture.
Inventors: Sarvetnick, Nora (San Diego, CA); Kritzik, Marcie (La Jolla, CA)
Assignee: The Scripps Research Institute (La Jolla, CA)
Date of First Priority Issue: Monday December 13th, 1999
Membrane for in guided tissue regeneration
Patent Number: 6752834Disclosed is a matrix that is useful for administration of living stem cells particularly for treatment of bone or cartilage injuries. The matrix is comprised primarily of collagen II and is compatible with a variety of stem cell technologies. This patent is useful for numerous applications.
Inventors: Geistlich, Peter (Stanstaad, CH); Eckmayer, Zdenek (Weinheim, DE); Schlosser, Lothar (Darmstadt, DE)
Assignee: Ed Geistlich Soehne AG Fuer Chemische Industrie (CH)
Date of First Priority Issue: Friday October 10th, 1997
Methods of treating disorders of the eye
Patent Number: 6750196This patent teaches expansion of retinal cells, and stem cells thereof, through the administration of proteins called neuroregulins. The patent is useful for treatment of a variety of ocular degenerative diseases.
Inventors: Reh, Thomas A. (Seattle, WA); Marchionni, Mark A. (Arlington, MA); McCabe, Kathryn L. (Seattle, WA); Bermingham-McDonogh, Olivia (Watertown, MA); Mahanthappa, Nagesh K. (Cambridge, MA); Gwynne, David I. (Beverly, MA)
Assignee: Acorda Therapeutics (Hawthorne, NY)
Date of First Priority Issue: Monday March 27th, 1995
Methods of identifying compounds for regulating muscle mass or function using vasoactive intestinal peptide receptors
Patent Number: 6750194This patent covers expansion of muscle mass through the use of vasoactive intestinal peptide receptors (VPAC)agonists. The activity of such agonists on stem cells are only beginning to be identified, and I am sure this area is ripe for expansion...for example, what do such agonists do on neural stem cells?
Inventors: Isfort, Robert Joseph (Fairfield, OH); Sheldon, Russell James (Fairfield, OH)
Assignee: The Procter & Gamble Company (Cincinnati, OH)
Date of First Priority Issue: Monday October 23rd, 2000
Implantable artificial organ and physiological monitoring system
Patent Number: 6750055This patent covers an implantable culture system that uses islet cells and/or stem cells for treatment of diabetes. What is interesting about this patent is that it actually involves a mechanism of detecting insulin so that the culture system and other additions to the body can be perform in order to maintain homeostatic insulin concentrations. This patent is useful for small biotechs...
Inventors: Connelly, Patrick R. (Rochester, NY); Weiner, Michael L. (Webster, NY)
Assignee: Biomed Solutions LLC (West Henrietta, NY)
Date of First Priority Issue: Wednesday March 7th, 2001
Method of cell culture using neurturin
Patent Number: 6743628This patent teaches how to expand neuronal stem cells through administration of the protein neurturin. The patent seems to be restricted to in vitro use.
Inventors: Johnson, Jr., Eugene M. (St. Louis, MO); Milbrandt, Jeffrey D. (St. Louis, MO); Kotzbauer, Paul T. (St. Louis, MO); Lampe, Patricia A. (St. Louis, MO)
Assignee: Washington University (St. Louis, MO)
Date of First Priority Issue: Monday August 28th, 1995