Patents
Treatment of brain damage
Patent Number: 6569421This patent teaches how to treat neurological damage through administration of stem cells into the contralateral hemisphere of the brain.
Inventor: Hodges, Helen (London, GB)
Assignee: Reneuron Limited (GB)
Date of First Priority Issue: Wednesday March 29th, 2000
Systems and methods of use for delivering beneficial agents for revascularizing stenotic bypass grafts and other occluded blood vessels and for other purposes
Patent Number: 6569147This patent teaches methods of administering cells and fluids in order to prevent inflammation and induce regeneration in areas of stent placement.
Inventors: Evans, Douglas G. (Downingtown, PA); Nash, John E. (Chester Springs, PA)
Assignee: Kensey Nash Corporation (Exton, PA)
Date of First Priority Issue: Friday July 26th, 1996
Methods for mobilizing hematopoietic progenitor cells from bone marrow into peripheral blood in a patient in need of chemotherapy
Patent Number: 6566335This patent teaches ways of mobilizing hematopoietic stem cells by administration of angiotensin I and/or II and/or analogues thereof.
Inventors: Rodgers, Kathleen E. (Long Beach, CA); DiZerega, Gere (Pasadena, CA)
Assignee: University of Southern California (Los Angeles, CA
Date of First Priority Issue: Monday May 11th, 1998
Protein-induced tissue morphogenesis
Patent Number: 6565843This patent teaches the use of the protein osteogenic protien-1 (OP-1) for the induction of tissue differentiation from stem cells. The invention is aimed primarily at induction of bone formation from osteogenic precursor cells.
Inventors: Cohen, Charles M. (Medway, MA); Kuberasampath, Thangavel (Medway, MA); Pang, Roy H. L. (Medway, MA); Oppermann, Hermann (Medway, MA); Rueger, David C. (West Roxbury, MA)
Assignee: Curis, Inc. (Cambridge, MA)
Date of First Priority Issue: Sunday March 11th, 2001
Differentiation of human embryonic germ cells
Patent Number: 6562619This patent teaches the utilization of ligands that activate gp130 for the induction of differentiation of embryonic germ stem cells.
Inventors: Gearhart, John D. (Baltimore, MD); Shamblott, Michael Joseph (Baltimore, MD)
Assignee: The Johns Hopkins University School of Medicine (Baltimore, MD)
Date of First Priority Issue: Monday March 31st, 1997
Treatment for diabetes
Patent Number: 6558952This patent teaches how to induce endogenous islet stem cells to multiply through administration of gastrin together with a ligand of the EGF receptor such as TGF alpha. One of the principles behind the current company doing clinical trials with this, Dr Tony Cruz, is also involved in the company Stem Cell Therapeutics, which is performing clinical trials with exogenous agents that stimulate...
Inventors: Parikh, Indu (Chapel Hill, NC); Lane, Anne (Westmount, CA); Nardi, Ronald V. (Mahwah, NJ); Brand, Stephen J. (Lincoln, MA)
Assignee: Waratah Pharmaceuticals, Inc. (Quebec, CA); The General Hospital Corporation (Boston, MA)
Date of First Priority Issue: Thursday July 30th, 1998
Stem cell inhibitor
Patent Number: 6558925This invention covers a composition of matter consisting of polypeptides that inhibit stem cell proliferation. This invention is useful for protecting stem cells during administration of chemotherapy or radiotherapy.
Inventors: Graham, Gerard (Glasgow, GB); Pragnell, Ian (Glasgow, GB)
Assignee: Wyeth (Madison, NJ)
Date of First Priority Issue: Tuesday March 9th, 1993
Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
Patent Number: 6555374This patent seems to cover a composition of cells that is made of adipose tissue and hematopoietic tissue. The composition is useful for regeneration of a hematopoietic system after ablation. Additionally, this composition may have uses for the induction of angiogenesis. In some papers, the induction of angiogenesis by bone marrow stem cells requires large amounts of stem cells to be...
Inventors: Gimble, Jeffrey Martin (Chapel Hill, NC); Halvorsen, Juan-Di Chang (Holly Springs, NC); Wilkison, William O. (Bahama, NC)
Assignee: Artecel Sciences, Inc. (Durham, NC)
Date of First Priority Issue: Thursday August 19th, 1999
Method to distinguish hematopoietic progenitor cells
Patent Number: 6555324This patent covers methods for identifying hematopoietic stem cells based on expression of markers such as CD34, CD38, and various growth factor receptors.
Inventors: Olweus, Johanna (Fremont, CA); Lund-Johansen, Fridtjof (Fremont, CA); Terstappen, Leon Wmm (Palo Alto, CA)
Assignee: Becton Dickinson & Company (Franklin Lakes, NJ)
Date of First Priority Issue: Thursday November 4th, 1993
Pharmaceutical preparation for the treatment of topical wounds and ulcers
Patent Number: 6555118This patent covers extracts from certain plants for the regeneration of skin tissue after wounding. The patent is useful not only for generation of a new topical product, but also for identification of potentially novel stem cell stimulators found in the concoction.
Inventor: Niazi, Sarfaraz K (Deerfield, IL)
Assignee: Unknown Assignee(s)
Date of First Priority Issue: Thursday February 22nd, 2001