News Posts
Autoimmunity by non-Th1 cells
Minneapolis, MN - Old school immunology divided responses into Th1 (inflammatory, intracellular responses) and Th2 (antibody mediated, extracellular responses). Classical autoimmune diseases such as Type 1 Diabetes, multiple sclerosis, and rheumatoid arthritis were considered primarily Th1 type diseases. More recently, the "dogma" of Th1/Th2 immunity has been subjected to numerous critism...Wednesday May 23rd, 2007 @ 02:19:07 EST
Embryoid Bodies as Models of Embryogenesis
Philadelphia, Pennsylvania - Cellular positioning during embryogenesis is a complex process involving numerous soluble and cell surface bound factors. A recent paper (Rula et al. Cell autonomous sorting and surface positioning in the formation of primitive endoderm in embryoid bodies. Genesis. 2007 May 15;45(6):327-338) using artificially generated embryoid bodies to further investigate this...Thursday May 17th, 2007 @ 21:42:14 EST
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hTERT GFP for stem cell detection
Kyoto, Japan – The concept of each tissue containing resident stem cells is not new. For example, it is known that in the liver, hepatic epithelial cells expressing common markers for hepatic and stem cells such as CD90, CD44 and CD29 act as precursors, capable of generating new hepatic tissue following injury (Khuu et al. Epithelial cells with hepatobiliary phenotype: is it another stem...Thursday May 17th, 2007 @ 21:36:27 EST
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Embryonic Stem Cell for Tympanic Healing
Stockholm, Sweden - Otitis media (ear infection) occurs in many young children and sometimes results in perforation of the tympanic membrane. Although surgical treatments are available for perforated membranes, these are quite painful. In a recent study embryonic stem cells were used to accelerate healing of experimentally damaged tympanic membranes (Rahman et al. Healing time, long-term...Tuesday May 15th, 2007 @ 12:10:22 EST
Embryonic-like stem cells in marrow
Louisville, Kentucky - The presence of embryonic-like stem cells has been reported in cord blood as well as amiotic fluid. In a recent review (Kucia et al. Bone marrow-derived very small embryonic-like stem cells: Their developmental origin and biological significance. Dev...Tuesday May 15th, 2007 @ 10:56:00 EST
PGI2 Regulates Myogenesis
Atlanta, USA - Muscle satellite cells are located beneath the myofiber basal laminae (under the basement membrane surrounding each myofiber) and close to capillaries. They play a critical role in repair and turn over of muscle, acting as a supply of progenitor cells. In a recent paper (Bondesen et al. Inhibition of myoblast migration by prostacyclin is associated with enhanced cell...Monday May 14th, 2007 @ 22:27:10 EST
Olfactory Ensheathing Cells R Different Than Schwann Cells
Kingston, Canada - Olfactory ensheathing cells are a type of glial cell specific to the olfactory system. The primary purpose of the olfactory ensheathing cells is to induce remyelination of damaged nerves, as well as to allow for regeneration in specific circumstances. Numerous groups have used olfactory ensheathing cells for acceleration of spinal cord injury. For example, Dr...Monday May 14th, 2007 @ 18:34:25 EST
Oocytes from ES cells
Beijing, China - The generation of oocyte-like cells from embryonic stem cells is described in the current paper (Qing et al. Induction of oocyte-like cells from mouse embryonic stem cells by co-culture with ovarian granulosa cells. Differentiation. 2007 May 9). Following the previous example of neural coculture stimulating embryonic...Monday May 14th, 2007 @ 14:44:46 EST
Endotoxin decreases circulating EPC
Vienna, Austria - Circulating endothelial progenitor cell levels have been reported to increase with exercise, smoking cessation, as well as taking statin drugs...amongst other things. In a recent paper it was demonstrated that endotoxin induces a temporary (24 hr) decrease in the number of circulating endothelial progenitors (Mayr et al. Effects of low dose endotoxemia on endothelial...Monday May 14th, 2007 @ 14:32:08 EST
Pluripotency in the amnion
Pittsburgh, PA - It has previously been described that anmiotic stem cells can be isolated and contain numerous regenerative properties. In a recent paper (Miki et al. Identification of stem cell marker-positive cells by immunofluorescence in term human amnion. J Reprod Immunol. 2007 May 8) the characterization of stem cells from the...Monday May 14th, 2007 @ 14:20:32 EST