News Posts
Nose to Hair: Differentiation of Olfactory Stem Cells
Sydney Australia - In a study published in today's issue of Stem Cells, Australian scientists reported a unique methodology for coaxing olfactory adult stem cells to acquire the phenotype of cochlear hair cells. This finding is important because deafness results from loss of cochlear hair cells and the ability to generate these cells in vitro would conceptually open the door for cell...
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Lipid Stimulation of Mesenchymal Differentiation
Seoul South Korea -
Jeon et al published today in the online version of the Journal of Cell Sciences that exposure of mesenchymal stem cells to the lipid sphingosylphosphorylcholine (SPC) induces differentiation into smooth muscle cells in a paper entitled
"Sphingosylphosphorylcholine induces differentiation of human mesenchymal stem cells into smooth-muscle-like cells through a
Electrical signals inducing stem cell differentation
Saitama Japan- In today's issue of the journal Stem Cells, Yamada et al reported that electrical stimulation of embryonic stem cells resulted in induction of differentiation into the neural lineage. In a paper entitled "Electrical stimulation modulates fate determination of differentiating embryonic stem cells", the authors demonstrated that embryonic stem cells differentiated by electrical...
Stromal-Like Environment Critical to Stem Cell Expansion
St. Louis, MO-
It is long been suggested that the appropriate imitation of in vivo microenvironments is critical to successful culture, expansion, and differentiation of stem cells.
In a paper which appeared in the Nov 9 online issue of Blood (Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34... Durham, North Carolina
Chute et al reported today that administration of mouse endothelial cells to irradiated B6 recipients was capable of accelerating hematopoietic reconstitution after sublethal and lethal irradiation.
In a paper entitled "Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice" published in today's... LONDON UK
Researchers in the UK have published in today's online version of the journal Nature (Maclaren et al. Retinal repair by transplantation of photoreceptor precursors, Nature. 2006 Nov 8.) an important finding in regards to stem cell therapy of photoreceptor loss
It was known in the art that transplantation of a wide variety of stem... Singapore-
Scientists at Viacell announced the ability of unrestricted somatic stem cells (USSC) to enhance migration and repopulation of hematopoietic stem cells in an animal model through secretion of the stem cell chemotactic factor SDF-1.
Chan et al in a publication titled "ENHANCED IN VIVO HOMING OF UNCULTURED AND... London, Canada
Researchers at the University of Western Ontario have published a paper in the October 15th, 2006, issue of the Journal of Cell Sciences (Karamboulas C et al, HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage. J Cell Sci. 2006 Oct 15;119(Pt 20):4305-14) describing mechanisms by which inhibition of histone... London UK
One of the major limitations of stem cell transplantation is the need to overcoming allogeneic barriers. The generation of stem cells from already differentiated tissue would significantly revolutionize the area of stem cell therapeutics.
In a paper published today (Abuljadayel et al. Infusion of autologous retrodifferentiated stem cells into patients with beta-thalassemia... Frankfurt, Germany
The concept of utilizing bone marrow cells to decrease scar tissue and improve patient prognosis after myocardial infarction has been previously tested clinically in patients. The majority of previous trials involved administration of autologous bone marrow within a certain time frame (usually 2-12 days) after the myocardial infarct. The reason for this is that...
Endothelial Stimulation of Hematopoietic Engraftment
Synchronization of Differentiation is Key
Stem Cells Follow The Leader
Modulation of Histone Deacetylases For Generating Heart Tissue
Clinical Trial of “Retro-Differentiated” Stem Cells: A Novel Way to Generate Autologous Stem Cells
Clinical Trial Demonstrating Benefit of Bone Marrow Stem Cells Administered > 3 Months Post Infarction